1996 OPEN FORUM Abstracts
Effects of Smoking Intervention: The Lung Health Study'
Paul D. Scanlon, M Monday, November 4, 1996
The Lung Health Study was an NIH-funded clinical trail evaluating the effectiveness of aggressive intervention for smokers with mild to moderate obstructive airways disease. Five thousand, eight hundred eight-seven participants were enrolled at 10 clinical centers. Those randomized to intervention received aggressive smoking cessation counseling, nicotine replacement, and inhaler therapy with either bronchodilator (ipratropium bromide) or placebo. This intervention resulted in improved lung function over the course of five years of follow up. Published results of the Lung Health Study will be reviewed along with the effects of smoking cessation on lung function, including the rates of decline in lung function comparing continuing smokers and quitters. Predictors of change in lung function will also be reviewed.