The Science Journal of the American Association for Respiratory Care

1998 OPEN FORUM Abstracts

PROSPECTIVE RANDOMIZED DOUBLE-BLIND CROSSOVER STUDY ON THE EFFECTS OF OXYGEN ON ANALYTICAL PERFORMANCE IN NORMOXIC SUBJECTS

Karl Knoblauch CRTT, RCP Meritcare Hospital Fargo, ND Jill Kielty CRTT Meritcare Hospital Fargo, ND

BACKGROUND: A new trend, in some countries, is to frequent "oxygen bars" to inhale pure oxygen for a prepaid amount of time. The customers claim to have increased energy and increased cognitive clarity. (Goldstein, Science World 1996; 53: 7(1)) (Scott, Advance 1997; Vol 10; N26: 5(1)) A review of the literature has not found studies which validate these claims, and no short term cognitive effects of increased oxygen consumption in normoxic people are known.

Methods: Twenty subjects were enrolled for this random double-blind study. Initial oxygen saturations, with a Nellcor Pulse Oximeter, were taken to determine normoxemia. They were then blinded and randomly assigned to one of two groups. Each group took the analytical portion of the Graduate Record Exam (GRE) twice. The software for the GRE was obtained from PowerPrep software. Group One: while taking the first GRE the subjects were assigned oxygen via nasal cannula (NC) @ 31pm or compressed air via NC @ 31pm. For the second GRE, the subjects did not receive a compressed gas. Group Two: while taking the first GRE; the subjects did not receive a compressed gas. For the second GRE, the subjects were assigned oxygen via NC @ 31pm, or compressed air via NC @ 31pm.* Results: Repeated measures ANOVA showed no significant difference among the treatment in Group One (Wilks' Lambda p=0.3412) or in Group Two (Wilks' Lambda p=0.7293). CONCLUSION: We found no relationship between the two inspired gases and the test results.

*Study Design Group

First Group Oxygen 31pm or No compressed gas

Compressed air @ 31pm

Second Group No compressed gas Oxygen @ 31pm or

Compressed air @ 31pm

The 44th International Respiratory Congress Abstracts-On-DiskĀ®, November 7 - 10, 1998, Atlanta, Georgia.

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