The Science Journal of the American Association for Respiratory Care
Background: Several actuator devices for delivering aerosol from metered-dose inhalers (MDI) during mechanical ventilation are designed to direct the ?plume? of aerosol away from the patient, into the oncoming inspiratory gas flow.
Methods: To determine whether directing the plume from the MDI away from the patient improves aerosol delivery, four puffs of albuterol (360
Results: Firing the MDI towards the patient improved aerosol delivery to the bronchi with each device tested. Conclusion: During mechanical ventilation, all devices tested delivered more albuterol to the bronchi when the output of the MDI was directed towards the patient. Devices designed to fire the plume away from the patient (ACE, Optivent, Medispacer) were more efficient when directing the MDI output towards the patient.