The Science Journal of the American Association for Respiratory Care

2008 OPEN FORUM Abstracts

EVALUATION OF A DIGITAL TCPCO2 SENSOR AND ITS CORRELATION TO ABG PCO2 MEASUREMENTS DURING NEONATAL HIGH FREQUENCY OSCILLATORY VENTILATION

Daniel D. Rowley1, Timothy E. Hicks1, Janet Glass1, Tamara Wheeler1, Frank J. Caruso1



Background: Obtaining arterial blood gases (ABGs) for measuring PaCO2 can be painful to patients and time consuming and hazardous for healthcare providers. In an attempt to reduce risks associated with ABG draws, as well as to provide a method by which clinicians may monitor PCO2 objectively, we evaluated the SenTec CO-OXSYS™ Digital Sensor for clinical accuracy during neonatal High Frequency Oscillatory Ventilation (HFOV).

Methods:
Neonatal patients on HFOV requiring an ABG for clinical indications unrelated to the SenTec monitor's evaluation were randomly and prospectively identified. Patient demographic information was obtained and recorded while the SenTec sensor self-calibrated. Following a successful sensor calibration, the digital sensor was applied to each patient using a skin sensitive multi-site attachment ring per manufacturer guidelines. Fifteen minutes following sensor application, an ABG was obtained and the concurrently displayed TCPCO2 measurement on the SenTec monitor was recorded. The ABG sample was subsequently analyzed using a Siemens Rapidpoint 405 analyzer. The measured PaCO2 was recorded next to the corresponding TCPCO2.

Results:
64% of our samples were obtained from very low birth weight neonates requiring vasopressors at the time of sample analysis. We found clinically acceptable correlation between the TCPCO2 and PaCO2 measurements. R2=0.807, p=<0.001. Refer to graph:

Conclusions:
The SenTec TCPCO2 digital sensor yielded excellent correlation when compared to ABG PaCO2 measurements and may be used as a surrogate for ABG PaCO2 determination. We intend to conduct a clinical trial using the SenTec Digital Sensor to assist clinicians in the objective determination of initial amplitude (ΔP) setting during the initiation of neonatal HFOV.