The Science Journal of the American Association for Respiratory Care

2009 OPEN FORUM Abstracts

VENTILATORY RESPONSE DURING CARDIOPULMONARY EXERCISE TESTING IN PEDIATRIC PATIENTS WITH AND WITHOUT CONGENITAL HEART DISEASE

Carl D. Mottram, Amber N. Loiacono, Michael Legesse, Simon Zzimbe, David Driscoll; Pulmonary and Critical Care, Mayo Clinic, Rochester, MN

Background: The ventilatory response during cardiopulmonary exercise testing has been fairly well characterized in the adult patient population. However it has not been well defined in the pediatric subject and in particular the pediatric subject with congenital heart disease. The adult subject’s minute ventilation increases throughout exercise to meet metabolic demand. In the adult the kinetics of minute ventilation recruitment is by increasing tidal volume to approximately 50% of the subject’s vital capacity with maximal breathing frequencies increasing to 36 (+ 9.2)1. We would like to identify the ventilatory recruitment strategies in the pediatric patient. Hypothesis: The ventilatory response to exercise in the pediatric population with and without congenital heart disease is similar and the same as the adult subject. Method: A retrospective review of the cardiopulmonary exercise test results from 150 pediatric patients (ages 10-16 yrs) will be conducted. 75 patients with a non-cardiac working diagnosis and 75 patients who have a history of congenital heart disease. Conclusion: Pediatric patients with a working non-cardiac diagnosis and pediatric patients with a diagnosis of cardiac origin show no significant difference between their ventilatory recruitment strategies in response to exercise. Even though there was a statistically significant difference in the Vtmax/FVC ratio it is relatively small and of no clinical significance. The minute ventilation recruitment strategy was also very similar to the strategies described in the adult population; although our data showed a slightly higher RRmax and lower Vtmax/FVC ratio. 1.Blackie S P, Fairbarn M S, McElvaney N G, et al. Normal values and ranges for ventilation and breathing pattern at maximal exercise. Chest 1991;100;136-142 Sponsored Research - None

Results

You are here: RCJournal.com » Past OPEN FORUM Abstracts » 2009 Abstracts » VENTILATORY RESPONSE DURING CARDIOPULMONARY EXERCISE TESTING IN PEDIATRIC PATIENTS WITH AND WITHOUT CONGENITAL HEART DISEASE