The Science Journal of the American Association for Respiratory Care

2011 OPEN FORUM Abstracts

AEROSOL DRUG DELIVERY VIA SVN AND RESUSCITATION BAGS TO PATIENTS WITH TRACHEOSTOMY

Arzu Ari, Robert Harwood, Meryl Sheard, James B. Fink; Division of Respiratory Therapy, Georgia State University, Atlanta, GA

BACKGROUND: Literature on aerosol delivery to patients with tracheostomy is limited. The purpose of this study was to evaluate aerosol drug delivery to patients with tracheostomy using different brands of resuscitation bags. METHODS: An upper airway of a teaching manikin was intubated with a tracheostomy tube (Portex) of 8 mm ID, and a collecting filter (Respirgard II) placed between the trachea and a passive test lung. Three different brands of resuscitation bags (Ambu Inc, Westmed and Smiths Medical) were ventilated with 2 hands at a rate of 12 bpm. A jet nebulizer (eValueMed, Trianim), which was placed between the bag and patient airway with a 15 mm adapter and 6 inches of 22 mm ID aerosol tubing, was operated at 8 lpm O2 to administer albuterol sulfate (2.5 mg/3mL). Each condition was repeated in triplicate (n=3). Drug was eluted from the filter and analyzed with spectrophotometry (276 nm). Descriptive statistics and one-way ANOVA were used for data analysis at the significant level of 0.05 (p < 0.05). RESULTS: The table shows inhaled mass (mean ± SD) and percentage of nominal dose delivered distal to the trachea. While aerosol deposition ranged from 11.9% to 15%. Differences among resuscitation bags in both inhaled mass (p=0.217) and inhaled mass percent (p=0.218) were not significant. CONCLUSION: In this model of a tracheotomized adult, the efficiency of aerosol deposition via different resuscitation bags with a SVN was similar. Further studies are warranted to establish inhaled dose with different types of aerosol generators and resuscitator bags. Sponsored Research – None