The Science Journal of the American Association for Respiratory Care

2012 OPEN FORUM Abstracts


I-Ling Chen1, Hsiu-Lin Chen1,3, Ko-Shin Chen3, Zen-Kong Dai2,3; 1Respiratory Therapy, Kaohsiung Medical University, Kaohsiung, Taiwan; 2Faculty of Medicine,College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; 3Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan

Objective. With advances in medical technology, the survival rate of low birth weight premature infants gradually raises in recent years. However, the complications of these survived infants might increase at the same time, especially chronic lung disease (CLD). Therefore, CLD in premature infants becomes an important issue in neonatology. The goal of this study is to evaluate pulmonary function of premature infants with and without CLD who were admitted to neonatal intensive care unit of Kaohsiung Medical University Hospital in southern Taiwan with agreement of infants’ parents. Patients and methods. Premature infants with a gestational age of less than 37 weeks needed respiratory support soon after birth were enrolled. The medical condition and respiratory supports were recorded during their stay of hospital. The study infants have received pulmonary function test once before discharge. Functional residual capacity (FRC) and ventilation indices were measured with a multiple-breath washin/washout technique using SF6 as a tracer gas.(Infant pulmonary function testing system, EXHALYZER® D, ECO MEDICS) Results. There were 22 premature infants performing pulmonary function test before discharge. No infant needs oxygen at discharge. The mean gestational age is 30.4 ±2.9 weeks, and the mean birth weight is 1597g± 660g. The mean age at checking lung function is 34.3 ± 33.1 days. FRC (ml) is significantly related to infants’ weight and body length. When CLD is defined as a need for supplemental oxygen at the postconceptional age of 36 weeks, the FRC is not significantly different in infants without CLD (n=13) than with CLD (n=9) (FRC 22.5±10.6 ml/kg with CLD vs. 26.0±6.5 ml/kg without CLD, p=0.171). Gender, antenatal steroid, patent ductus arteriosus, diuretics or aminophylline use did not have significant effects on FRC data in ml per kg. Conclusion. Conducting infant pulmonary function test on those premature infants who prepare to discharge from hospital is practicable and it doesn’t have any adverse effect. The larger sample size is needed. Sponsored Research - None