The Science Journal of the American Association for Respiratory Care

2012 OPEN FORUM Abstracts

COMPARISON OF AEROSL DELIVERY USING THE AEROGEN MICROPUMP AND JET NEBULIZER IN A CLOSED-SYSTEM VENTILATOR CIRCUIT.

Kimberly Farney1, Brandon Kuehne1, Jennah Hollen2, Laurie Gibson3; 1NICU, Nationwide Childrens Hospital, Columbus, OH; 2Respiratory Care, Nationwide Children’s Hospita, Columbus, OH; 3Radiology, Nuclear Medicine Secion, Nationwide Children’s Hospita, Columbus, OH

Background There has been discussion on the efficacy of aerosolized medication devices given through closed-system ventilator circuits. The jet nebulizer and the micro pump aerosol generator have been an acceptable method of aerosolized medication delivery systems in the hospital setting. However, little is known about how much aerosolized medication is actually delivered to the patient when using the jet nebulizer and the micro pump in-line through a closed-system ventilator circuit. Methods Testing was performed through an Airlife Care fusion Infant Respiratory (RT4851-12) closed-system circuit connected to an Avea Ventilator utilizing a Bio-med™ device test lung. Each test disbursed a 3 ml of TC 99mTC DTDA as our aerosol. The Aerogen micro pump and Misty-Neb™ jet nebulizer were placed in line at the temperature probe on the inspiratory limb of the ciricuit approximately 18 inches from the patient wye and patient effort was simulated at a 0.45 minute volume. The built in nebulizer function of the Avea ventilator was used to drive the Misty-Neb™ jet nebulizer. All nebulizer sessions were performed over the duration of medication. All circuits were then placed under a GE Infinia Hawkeye Gamma Camera. Results Data was analyzed from 15 sessions. The average medication delivery toward the patient with the micro pump was 3.45% ±2.13 (n=9). The average medication delivery toward the patient with the jet nebulizer was 0.78% ±0.53 (n=6). Single factor analysis of variation (ANOVA) yielded a P= 0.008 between the micro pump and the jet nebulizer. Conclusion With the intubated patient there was a statistically significant difference in delivery of the aerosolized medication toward the patient using the Aerogen Micropump at the temperature probe compared to the Misty-Net™. Sponsored Research - None Jet Nebulizer and Circuit